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ACE Inhibitors

Angiotensin-Converting Enzyme (ACE) Inhibitors are pharmaceuticals that are used in the treatment of hypertension and congestive heart failure. Their uses include the prevention of cardiovascular disorders and left ventricular dysfunction. They have been shown to be the first choice in the treatment of these disorders. ACE inhibitors can be combined with diuretics in the control of hypertension and in chronic heart failure. The inhibitors lower arteriolar resistance, increasing venous capacitance, cardiac output and index. They can increase stroke work and volume, while lowering renovascular resistance. They can also lead to the increased excretion of sodium in the urine.

There can be some adverse reactions to the drug including headaches, dizziness, fatigue, nausea and coughing. There can also be some more severe types of reactions to the treatment. In these cases, the ACE inhibitors should be replaced by alternative types of pharmaceuticals depending on the problems associated with the inhibitors. ACE Inhibitors are usually not prescribed for pregnant women as they can cause birth defects in unborn children.

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